Ceramide 3-d3 [CAS 1354806-91-9]
Ceramide 3-d3 [CAS 1354806-91-9]
SKU:QM-0123348
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Product Details
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Description
Ceramide 3-d3 (N-Stearoyl phytosphingosine-d3) is deuterium labeled Ceramide 3. C18 Phytoceramide (t18:0/18:0) (Cer (t18:0/18:0) ) is a bioactive sphingolipid found in the stratum corneum of Saccharomyces cerevisiae, wheat grain, and mammalian epidermis. Cer (t18:0/18:0) consists of a phytosphingosine backbone amine linked to a C18 fatty acid chain. Cer (t18:0/18:0) has the function of regulating apoptosis, cell differentiation, proliferation of smooth muscle cells and inhibition of mitochondrial respiratory chain. It also suppresses the expression of allergic cytokines IL-4, TNF-α, and transcription factors c-Jun and NF-κB in histone-stimulated mouse skin tissue. Formulations containing cer (t18:0/18:0) have been used as skin protectants in cosmetics as they reduce water loss and prevent epidermal dehydration and irritation[1].
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CAS Number
[1354806-91-9]
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Molecular Formula
C36H70D3NO4
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Molecular Weight
586.99
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Smiles
OC[C@@H]([C@H](O)[C@H](O)CCCCCCCCCCCCCC)NC(CCCCCCCCCCCCCCCCC([2H])([2H])[2H])=O
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Target
Biochemical Assay Reagents; Isotope-Labeled Compounds
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Shipping Conditions
Room temperature
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Ceramide 3-d3 [CAS 1354806-91-9]
Ceramide 3-d3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.