1 1

Vepafestinib [CAS 2129515-96-2]

Vepafestinib [CAS 2129515-96-2]

Size

QM-0144182-01

£551.80 GBP
Sale Sold out

Request quote or documents

View full details

Product Details

  • Description

    Vepafestinib (TAS0953/HM06) is a next-generation brain-penetrant, selective and orally active RET inhibitor with an IC50 value of 0.33 nM. Vepafestinib inhibits the phosphorylation of RET and its downstream signaling pathways, thus blocking the growth and signal transduction of tumor cells and inducing cell cycle arrest and apoptosis. Vepafestinib can be used in the research of various RET-driven cancers, such as non-small cell lung cancer, thyroid cancer and other disease areas[1].

  • CAS Number

    [2129515-96-2]

  • Molecular Formula

    C26H30N6O3

  • Molecular Weight

    474.55

  • Smiles

    O=C(C1=C(C#CCN2CCOCC2)N(C3(C)CC3)C4=NC=NC(N)=C41)NC5=CC=C(COC)C=C5

  • Target

    Apoptosis; RET

  • Purity

    98.61

  • Solubility

    DMSO : 50 mg/mL (ultrasonic)

  • Storage Conditions

    -20°C, 3 years (Powder)

  • Shipping Conditions

    Blue Ice
Learn more
Variant Variant total Quantity Price Variant total
5 mgQM-0144182-01
5 mgQM-0144182-01
£551.80/ea		 £0.00
£551.80/ea £0.00
10 mM - 1 mLQM-0144182-02
10 mM - 1 mLQM-0144182-02
£574.88/ea		 £0.00
£574.88/ea £0.00
10 mgQM-0144182-03
10 mgQM-0144182-03
£803.30/ea		 £0.00
£803.30/ea £0.00
25 mgQM-0144182-04
25 mgQM-0144182-04
£1,405.94/ea		 £0.00
£1,405.94/ea £0.00
50 mgQM-0144182-05
50 mgQM-0144182-05
£1,879.79/ea		 £0.00
£1,879.79/ea £0.00
100 mgQM-0144182-06
100 mgQM-0144182-06
£2,510.38/ea		 £0.00
£2,510.38/ea £0.00
View cart
0

Total items

£0.00

Product subtotal

Taxes, discounts and shipping calculated at checkout.
View cart

Related Products

Other industry favorites

Vepafestinib [CAS 2129515-96-2]

Vepafestinib is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.