Ceritinib dihydrochloride (Standard) [CAS 1380575-43-8]
Ceritinib dihydrochloride (Standard) [CAS 1380575-43-8]
SKU:QM-0007716-01
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Product Details
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Description
Ceritinib dihydrochloride (Standard) is the analytical standard of Ceritinib dihydrochloride. This product is intended for research and analytical applications. Ceritinib dihydrochloride (LDK378 dihydrochloride) is a selective, orally bioavailable and ATP-competitive ALK tyrosine kinase inhibitor with an IC50 of 200 pM. Ceritinib dihydrochloride (LDK378 dihydrochloride) also inhibits IGF-1R, InsR, and STK22D with IC50 values of 8, 7, and 23 nM, respectively. Ceritinib dihydrochloride (LDK378 dihydrochloride) shows great antitumor potency[1][2].
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CAS Number
[1380575-43-8]
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Molecular Formula
C28H38Cl3N5O3S
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Molecular Weight
631.06
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Smiles
CC(C)OC1=CC(C2CCNCC2)=C(C)C=C1NC3=NC=C(Cl)C(NC4=CC=CC=C4S(=O)(C(C)C)=O)=N3.[H]Cl.[H]Cl
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Target
Anaplastic lymphoma kinase (ALK) ; IGF-1R; Insulin Receptor; Reference Standards
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Shipping Conditions
Room temperature
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Ceritinib dihydrochloride (Standard) [CAS 1380575-43-8]
Ceritinib dihydrochloride (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.