Cerivastatin [CAS 145599-86-6]
Cerivastatin [CAS 145599-86-6]
SKU:QM-0061260
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Product Details
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Description
Cerivastatin is a synthetic lipid-lowering agent and a highly potent, well-tolerated and orally active HMG-CoA reductase inhibitor, with a Ki of 1.3 nM/L. Cerivastatin reduces low-density lipoprotein cholesterol levels. Cerivastatin also inhibits proliferation and invasiveness of MDA-MB-231 cells, mainly by RhoA inhibition, and has anti-cancer effect[1][2][3].
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CAS Number
[145599-86-6]
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Molecular Formula
C26H34FNO5
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Molecular Weight
459.55
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Smiles
O=C(O)C[C@H](O)C[C@H](O)/C=C/C1=C(C2=CC=C(F)C=C2)C(COC)=C(C(C)C)N=C1C(C)C
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Target
Ferroptosis; HMG-CoA Reductase (HMGCR)
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Hazard Statement
H302-H315-H319-H335
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Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Cerivastatin [CAS 145599-86-6]
Cerivastatin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.