CGP 12177 (hydrochloride) [CAS 64208-32-8]
CGP 12177 (hydrochloride) [CAS 64208-32-8]
SKU:QM-0081206-01
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Product Details
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Description
CGP 12177 ((±) -CGP 12177) hydrochloride is a β-Adrenergic receptor (β-AR) ligand. CGP 12177 hydrochloride is a β3-AR (Ki = 88 nM) agonist with β1/β2-AR (Ki = 0.9 nM for β1; Ki = 4 nM for β2) antagonist action. CGP 12177 hydrochloride exhibits partial agonist properties for α1-AR in rat pulmonary artery. CGP 12177 hydrochloride regulates the expression of ucp and leptin genes in NMRI mice adipose tissues. CGP 12177 hydrochloride can be used for cardiovascular and metabolic disease research[1][2][3][4].
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CAS Number
[64208-32-8]
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Molecular Formula
C14H22ClN3O3
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Molecular Weight
315.8
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Smiles
O=C1NC2=C(OCC(O)CNC(C)(C)C)C=CC=C2N1.Cl
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Target
Adrenergic Receptor
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Isoform
α adrenergic receptor; β adrenergic receptor
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Purity
99.69
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Solubility
DMSO : 10 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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CGP 12177 (hydrochloride) [CAS 64208-32-8]
CGP 12177 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.