Cilastatin [CAS 82009-34-5]
Cilastatin [CAS 82009-34-5]
SKU:QM-0075693-01
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Product Details
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Description
Cilastatin (MK0791) is a reversible, competitive renal dehydropeptidase I inhibitor with an IC50 of 0.1 μM. Cilastatin inhibits the bacterial metallob-lactamase enzyme CphA with an IC50 of 178 μM. Cilastatin is an antibacterial adjunct[1][2][3].
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CAS Number
[82009-34-5]
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Molecular Formula
C16H26N2O5S
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Molecular Weight
358.45
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Smiles
O=C(O)/C(NC([C@@H]1C(C)(C)C1)=O)=C/CCCCSC[C@H](N)C(O)=O
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Target
Antibiotic; Bacterial
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Isoform
β-lactam
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Concentration
10mM
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Purity
99.91
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Solubility
1M NaOH : 100 mg/mL (ultrasonic; adjust pH to 12 with NaOH) |DMSO : 100 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Cilastatin [CAS 82009-34-5]
Cilastatin is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.