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Cinnamtannin D1 [CAS 97233-06-2]

Cinnamtannin D1 [CAS 97233-06-2]

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SKU:QM-0023919

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  • Description

    Cinnamtannin D1 is an orally active polyphenolic compound with immunosuppressive activity. Cinnamtannin D1 regulates the balance of Th17/Treg cells by inhibiting AHR expression. Cinnamtannin D1 reduces apoptosis and ROS in INS-1 cells and primary cultured murine islets induced by Palmitic acid (PA). Cinnamtannin D1 reduces Th17 cell differentiation via downregulating p-STAT3/RORγt and promotes Treg cell differentiation via upregulating p-STAT5/Foxp3. Cinnamtannin D1 exerts excellent anti-arthritic efficacy in collagen-induced arthritis (CIA) model of mice. Cinnamtannin D1 can be used for the study of rheumatoid arthritis (RA)[2].

  • CAS Number

    [97233-06-2]

  • Molecular Formula

    C45H36O18

  • Molecular Weight

    864.76

  • Smiles

    O[C@H]1[C@](OC2=CC(O)=C3)(C(C=C4)=CC(O)=C4O)OC(C=C5O)=C(C(O[C@@H]6C(C=C7)=CC(O)=C7O)=C5[C@H](C(C(O)=C8)=C(O[C@H](C(C=C9)=CC(O)=C9O)[C@H]%10O)C(C%10)=C8O)[C@H]6O)[C@@]1([H])C2=C3O

  • Target

    Apoptosis; Reactive Oxygen Species (ROS) ; STAT

  • Shipping Conditions

    Room temperature

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Cinnamtannin D1 [CAS 97233-06-2]

Cinnamtannin D1 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.