Clindamycin-13C, d3 [CAS 2140264-63-5]
Clindamycin-13C, d3 [CAS 2140264-63-5]
SKU:QM-0124244
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Product Details
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Description
Clindamycin-13C, d3 is the 13C- and deuterium labeled Clindamycin. Clindamycin is an orally active and broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin can inhibit bacterial protein synthesis, possessing the ability to suppress the expression of virulence factors in Staphylococcus aureus at sub-inhibitory concentrations (sub-MICs) . Clindamycin resistance results from enzymatic methylation of the antibiotic binding site in the 50S ribosomal subunit (23S rRNA) . Clindamycin decreases the production of Panton-Valentine leucocidin (PVL), toxic-shock-staphylococcal toxin (TSST-1) or alpha-haemolysin (Hla) . Clindamycin also can be used for researching malaria[1][2][3].
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CAS Number
[2140264-63-5]
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Molecular Formula
C17 13CH30D3ClN2O5S
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Molecular Weight
428.99
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Smiles
O=C([C@@H]1C[C@H](CN1[13C]([2H])([2H])[2H])CCC)N[C@@H]([C@@]2([H])O[C@@H]([C@@H]([C@H]([C@H]2O)O)O)SC)[C@@H](Cl)C
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Target
Antibiotic; Bacterial; Isotope-Labeled Compounds; Parasite
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Isoform
Plasmodium
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Purity
99.94
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Solubility
10 mM in DMSO|DMSO : 125mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Clindamycin-13C, d3 [CAS 2140264-63-5]
Clindamycin-13C, d3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.