Clozapine-d3 [CAS 1215691-72-7]
Clozapine-d3 [CAS 1215691-72-7]
SKU:QM-0122317
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Product Details
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Description
Clozapine-d3 (HF 1854-d3) is deuterium labeled Clozapine. Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine has high affinity for a number of neuroreceptors. Clozapine is a potent antagonist of dopamine D2 with a Ki of 75 nM. Clozapine inhibits the muscarinic M1 receptor and serotonin 5HT2A receptor with Kis of 9.5 nM and 4 nM, respectively[1][2][3]. Clozapine is also a potent and selective agonist at the muscarinic M4 receptor (EC50=11 nM) [1][2][3][4][5].
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CAS Number
[1215691-72-7]
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Molecular Formula
C18H16D3ClN4
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Molecular Weight
329.84
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Smiles
[2H]C(N1CCN(C2=NC3=CC(Cl)=CC=C3NC4=CC=CC=C42)CC1)([2H])[2H]
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Target
5-HT Receptor; Adrenergic Receptor; Dopamine Receptor; Isotope-Labeled Compounds; mAChR
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Isoform
5-HT2 Receptor
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Shipping Conditions
Room temperature
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Clozapine-d3 [CAS 1215691-72-7]
Clozapine-d3 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.