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CMP-5 (hydrochloride) [CAS 1030021-40-9]
CMP-5 (hydrochloride) [CAS 1030021-40-9]
SKU:QM-0058849
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Product Details
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Description
CMP-5 hydrochloride is a potent, specific, and selective PRMT5 inhibitor, while displays no activity against PRMT1, PRMT4, and PRMT7 enzymes. CMP-5 hydrochloride selectively blocks S2Me-H4R3 by inhibiting PRMT5 methyltransferase activity on histone preparations. CMP-5 hydrochloride prevents EBV-driven B-lymphocyte transformation but leaving normal B cells unaffected[1][2].
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CAS Number
[1030021-40-9]
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Molecular Formula
C21H22ClN3
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Molecular Weight
351.87
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Smiles
CCN1C2=C(C3=C1C=CC=C3)C=C(CNCC4=NC=CC=C4)C=C2.[H]Cl
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Target
Histone Methyltransferase
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Isoform
PRMT5
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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CMP-5 (hydrochloride) [CAS 1030021-40-9]
CMP-5 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.