Cortistatin-29 (reduced)
Cortistatin-29 (reduced)
SKU:QM-0199802-01
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Product Details
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Description
Cortistatin-29 is a neuropeptide. Cortistatin-29 alleviates neuropathic pain. Cortistatin-29 binds all somatostatin (SS) receptor subtypes with high affinity and shows IC50 values of 2.8 nM, 7.1 nM, 0.2 nM, 3.0 nM, 13.7 nM for SSTR1, SSTR2, SSTR3, SSTR4, SSTR5, respectively. Cortistatin-29 shows anti-fibrotic effects[1][2][3][4].
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Molecular Formula
C161H242N46O41S2
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Molecular Weight
3539.77
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Smiles
O=C([C@@H](NC([C@@H](N1)CCC1=O)=O)CCC(O)=O)N[C@H](C(N2[C@H](C(N3[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N4[C@H](C(N5[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N6[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)CS)=O)CO)=O)CO)=O)CC7=CC=CC=C7)=O)[C@@H](C)O)=O)CCCCN)=O)CC8=CNC9=CC=CC=C89)=O)CC%10=CC=CC=C%10)=O)CC%11=CC=CC=C%11)=O)CC(N)=O)=O)CCCCN)=O)CS)=O)CCC6)=O)CCCCN)=O)CCCCN)=O)CC(O)=O)=O)CCCNC(N)=N)=O)CC%12=CNC=N%12)=O)CCC5)=O)CCC4)=O)CCC(N)=O)=O)CCC(N)=O)=O)CC(C)C)=O)CCC3)=O)CCC2)=O)CCCNC(N)=N
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Target
Somatostatin Receptor
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Isoform
SSTR1; SSTR2; SSTR3; SSTR4; SSTR5
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Purity
98.12
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Solubility
H2O : 100 mg/mL (ultrasonic)
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Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
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Shipping Conditions
Blue Ice
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Cortistatin-29 (reduced)
Cortistatin-29 (reduced) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.