Cortistatin-8 [CAS 485803-62-1]
Cortistatin-8 [CAS 485803-62-1]
SKU:QM-0123846-01
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Product Details
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Description
Cortistatin-8 (CST-8; PCFWKTCK), a neuropeptide, is a GHS-R1a antagonist by counteracting the response of ghrelin on gastric acid secretion. Cortistatin-8 can modulate GH release from somatotroph cells. Cortistatin-8 is a synthetic CST-analogue devoid of any binding affinity to SST-R but capable to bind the GHS-R1a. Cortistatin-8 can exert antagonistic effects on ghrelin actions either in vitro or in vivo in animals[1].
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CAS Number
[485803-62-1]
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Molecular Formula
C47H68N12O9S2
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Molecular Weight
1009.25
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Smiles
O=C(N[C@@H]1CC2=CNC3=CC=CC=C23)[C@H](CC4=CC=CC=C4)NC([C@@]([H])(NC([C@@H]5CCCN5)=O)CSSC[C@H](NC([C@@]([H])(NC([C@@]([H])(NC1=O)CCCCN)=O)[C@@H](C)O)=O)C(N[C@@H](CCCCN)C(N)=O)=O)=O
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Target
GHSR
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Isoform
GHSR1a
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Purity
98.86
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Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Cortistatin-8 [CAS 485803-62-1]
Cortistatin-8 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.