CPI-455 (hydrochloride) [CAS 2095432-28-1]
CPI-455 (hydrochloride) [CAS 2095432-28-1]
SKU:QM-0056873-01
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Product Details
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Description
CPI-455 hydrochloride is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 hydrochloride mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents[1].
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CAS Number
[2095432-28-1]
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Molecular Formula
C16H15ClN4O
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Molecular Weight
314.77
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Smiles
N#CC1=C2NC(C3=CC=CC=C3)=C(C(C)C)C(N2N=C1)=O.[H]Cl
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Target
Histone Demethylase
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Isoform
KDM5
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Purity
99.95
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Solubility
DMSO : 8.33 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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CPI-455 (hydrochloride) [CAS 2095432-28-1]
CPI-455 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.