Crizotinib (Standard) [CAS 877399-52-5]

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SKU:QM-0156491-01

£127.38 GBP

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Product Details

Description
Crizotinib (Standard) is the analytical standard of Crizotinib. This product is intended for research and analytical applications. Crizotinib (PF-02341066) is an orally bioavailable, ATP-competitive ALK and c-Met inhibitor with IC50s of 20 and 8 nM, respectively. Crizotinib inhibits tyrosine phosphorylation of NPM-ALK and tyrosine phosphorylation of c-Met with IC50s of 24 and 11 nM in cell-based assays, respectively. Crizotinib is also a ROS1 inhibitor. Crizotinib has effective tumor growth inhibition[1][2][3].
CAS Number
[877399-52-5]
Molecular Formula
C21H22Cl2FN5O
Molecular Weight
450.34
Smiles
ClC1=C(F)C=CC(Cl)=C1[C@H](OC2=CC(C3=CN(N=C3)C4CCNCC4)=CN=C2N)C
Target
Anaplastic lymphoma kinase (ALK) ; Autophagy; c-Met/HGFR; Reference Standards; ROS Kinase
Shipping Conditions
Room temperature

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Variant	Variant total	Quantity	Price	Variant total
5 mgQM-0156491-01	5 mgQM-0156491-01 £127.38/ea	£0.00	Quantity	£127.38/ea	£0.00

10 mgQM-0156491-02	10 mgQM-0156491-02 £204.31/ea	£0.00	Quantity	£204.31/ea	£0.00

25 mgQM-0156491-03	25 mgQM-0156491-03 £297.86/ea	£0.00	Quantity	£297.86/ea	£0.00

50 mgQM-0156491-04	50 mgQM-0156491-04 £370.76/ea	£0.00	Quantity	£370.76/ea	£0.00

100 mgQM-0156491-05	100 mgQM-0156491-05 £466.75/ea	£0.00	Quantity	£466.75/ea	£0.00

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Crizotinib (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.