CRT0066101 (trihydrochloride) [CAS 1781742-22-0]
CRT0066101 (trihydrochloride) [CAS 1781742-22-0]
SKU:QM-0087351
Request quote or documents
![CRT0066101 (trihydrochloride) [CAS 1781742-22-0]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
CRT0066101 trihydrochloride is the trihydrochloride salt form of CRT0066101. CRT0066101 trihydrochloride is an orally active PKD inhibitor with IC50 values of 1 nM, 2.5 nM and 2 nM for PKD1, PKD2, and PKD3, respectively. CRT0066101 trihydrochloride is also an inhibitor for PIM2 with an IC50 of ~135.7 nM. CRT0066101 trihydrochloride exhibits anti-inflammatory activity in mice LPS (HY-D1056) -induced lung injury models, and has anticancer effects[1][2][3].
-
CAS Number
[1781742-22-0]
-
Molecular Formula
C18H25Cl3N6O
-
Molecular Weight
447.79
-
Smiles
[H]Cl.[H]Cl.[H]Cl.N[C@H](CC)CNC1=NC(C2=C(O)C=CC(C3=CN(C)N=C3)=C2)=NC=C1
-
Target
Apoptosis; Pim; PKD
-
Isoform
PIM2; PKD1; PKD2; PKD3
-
Shipping Conditions
Room temperature
-
Hazard Statement
H302-H315-H319-H335
-
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Related Products
- QM-0054453-01 Δ9-Tetrahydrocannabinolic acid [CAS 23978-85-0]
- QM-0053803 γ-Linolenic acid ethyl ester-d5
- QM-0052686-01 β-Phenyl GHB (sodium) [CAS 40951-19-7]
- QM-0051720-01 β-Phenylethyl β-D-glucoside [CAS 18997-54-1]
- QM-0049152-01 β-keto Phentermine (hydrochloride) [CAS 6946-08-3]
- QM-0048489-01 β-N-methylamino-L-alanine (hydrochloride) (Standard) [CAS 16012-55-8]
- QM-0022874 β-Prumycin hydrochloride [CAS 54612-74-7]
- QM-0008481-01 β-Methoxy 2C-B (hydrochloride) [CAS 98537-39-4]
- QM-0005999-01 β-Muricholic acid (Standard) [CAS 2393-59-1]
- QM-0161998-01 γ-Aminobutyric acid (Standard) [CAS 56-12-2]
Other industry favorites
- QM-0054453-01 Δ9-Tetrahydrocannabinolic acid [CAS 23978-85-0]
- QM-0053803 γ-Linolenic acid ethyl ester-d5
- QM-0143709-01 γ-Acetylenic GABA (hydrochloride) [CAS 103451-26-9]
- QM-0178574-01 β-Sitosterol acetate, 40% (contains Campesterol acetate) [CAS 915-05-9]
- QM-0061106-01 γ-D-Glutamylaminomethylsulfonic acid [CAS 90237-02-8]
- QM-0090052 β-Peltoboykinolic acid [CAS 24778-48-1]
- QM-0161999-01 γ-Aminobutyric acid-d6 [CAS 70607-85-1]
- QM-0162002-01 γ-Aminobutyric acid-13C4
- QM-0111443-01 β-Methylcholine (chloride) [CAS 2382-43-6]
- QM-0067514 γ-Secretase modulator 11 (hydrochloride) [CAS 2434630-30-3]
CRT0066101 (trihydrochloride) [CAS 1781742-22-0]
CRT0066101 (trihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.