Cudetaxestat [CAS 1782070-21-6]
Cudetaxestat [CAS 1782070-21-6]
SKU:QM-0148598-01
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Product Details
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Description
Cudetaxestat (BLD-0409; PAT-409) is an orally active and noncompetitive autotaxin (ATX) inhibitor. Cudetaxestat inhibits the activity of ATX, reduces the production of LPA, and thereby blocks the signal transduction of the ATX-LPA axis. Cudetaxestat can still maintain nanomolar-level biochemical efficacy even when the concentration of the LPC substrate increases. Cudetaxestat can be used for the study of various diseases related to LPA including fibrosis, tumor metastasis, inflammation and autoimmune diseases, etc[1][2].
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CAS Number
[1782070-21-6]
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Molecular Formula
C21H15Cl2F2N3O2S
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Molecular Weight
482.33
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Smiles
O=C(C1=C(F)C(SC2=C(N(C3=C2C=CC(Cl)=C3F)C4=CN(CCC)N=C4)Cl)=CC=C1)O
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Target
LPL Receptor; Phosphodiesterase (PDE)
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Isoform
Autotaxin
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Purity
98.32
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Solubility
DMSO : 250 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years (Powder)
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Shipping Conditions
Blue Ice
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Cudetaxestat [CAS 1782070-21-6]
Cudetaxestat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.