Cutamesine dihydrochloride [CAS 165377-44-6]
Cutamesine dihydrochloride [CAS 165377-44-6]
SKU:QM-0144949-01
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Product Details
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Description
Cutamesine (SA4503) dihydrochloride is a potent and selective sigma 1 receptor agonist with an IC50 of 17.4 nM in guinea pig brain membranes. Cutamesine dihydrochloride shows >100-fold less affinity for the sigma 2 receptor (IC50 of 1784 nM) . Cutamesine dihydrochloride has antidepressant effects[1][2].
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CAS Number
[165377-44-6]
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Molecular Formula
C23H34Cl2N2O2
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Molecular Weight
441.43
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Smiles
COC1=CC=C(CCN2CCN(CCCC3=CC=CC=C3)CC2)C=C1OC.Cl.Cl
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Target
Sigma Receptor
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Isoform
Sigma 1 Receptor; Sigma 2 Receptor
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Concentration
10mM
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Purity
98.05
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Solubility
DMSO : 30 mg/mL (ultrasonic; warming) |H2O : 100 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Cutamesine dihydrochloride [CAS 165377-44-6]
Cutamesine dihydrochloride is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.