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CX-5461 (Standard) [CAS 1138549-36-6]
CX-5461 (Standard) [CAS 1138549-36-6]
SKU:QM-0129548-01
£436.37 GBP
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Product Details
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Description
CX-5461 (Standard) is the analytical standard of CX-5461. This product is intended for research and analytical applications. CX-5461 is a potent and oral rRNA synthesis inhibitor. It inhibits RNA polymerase I-driven transcription of rRNA with IC50s of 142, 113, and 54 nM in HCT-116, A375, and MIA PaCa-2 cells, respectively[1].
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CAS Number
[1138549-36-6]
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Molecular Formula
C27H27N7O2S
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Molecular Weight
513.61
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Smiles
CC1=NC=C(CNC(C2=C3N(C4=NC(N5CCN(CCC5)C)=CC=C4C2=O)C6=C(S3)C=CC=C6)=O)N=C1
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Target
DNA/RNA Synthesis; Reference Standards
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Shipping Conditions
Room temperature
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CX-5461 (Standard) [CAS 1138549-36-6]
CX-5461 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.