Cyclic GMP (Standard) [CAS 7665-99-8]
Cyclic GMP (Standard) [CAS 7665-99-8]
SKU:QM-0003935-01
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Product Details
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Description
Cyclic GMP (Standard) is the analytical standard of Cyclic GMP. This product is intended for research and analytical applications. Cyclic GMP (cGMP), an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses[1][2][3][4].
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CAS Number
[7665-99-8]
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Molecular Formula
C10H12N5O7P
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Molecular Weight
345.21
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Smiles
O[C@@H]([C@H](N1C=NC2=C1N=C(N)NC2=O)O[C@@H]3CO4)[C@@H]3OP4(O)=O
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Target
Endogenous Metabolite; Reference Standards
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Purity
99.54
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Storage Conditions
-20°C, sealed storage, away from light and moisture
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Shipping Conditions
Blue Ice
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Cyclic GMP (Standard) [CAS 7665-99-8]
Cyclic GMP (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.