Cyclosporin A-13C2, d4
Cyclosporin A-13C2, d4
SKU:QM-0075039
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Product Details
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Description
Cyclosporin A-13C2, d4 (Cyclosporine A-13C2, d4; Ciclosporin A-13C2, d4) is a 13C labeled Cyclosporin A. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM[2]. Cyclosporin A also inhibits CD11a/CD18 adhesion[3].
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Molecular Formula
C60 13C2H107D4N11O12
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Molecular Weight
1208.62
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Smiles
CN(CC(N([C@H](C(N[C@]([H])(C(N([C@H](C(N[C@H](C(N[C@@H](C(N([C@@](CC(C)C)(C(N([C@H](C(N([C@@](C(C)C)(C(N([C@]1([C@@H]([C@@H](C/C=[13C]([2H])/[13C]([2H])([2H])[2H])C)O)[H])C)=O)[H])C)=O)CC(C)C)C)=O)[H])C)=O)C)=O)C)=O)CC(C)C)C)=O)C(C)C)=O)CC(C)C)C)=O)C([C@H](CC)NC1=O)=O
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Target
Isotope-Labeled Compounds
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Purity
95.21
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Solubility
10 mM in DMSO
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Cyclosporin A-13C2, d4
Cyclosporin A-13C2, d4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.