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CYM5442 (hydrochloride) [CAS 1783987-80-3]
CYM5442 (hydrochloride) [CAS 1783987-80-3]
SKU:QM-0058152
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Product Details
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Description
CYM5442 hydrochloride is a potent, highly-selective and orally active sphingosine 1-phosphate (S1P1) receptor agonist with an EC50 of 1.35 nM. CYM5442 hydrochloride is inactive against S1P2, S1P3, S1P4, and S1P5. CYM5442 hydrochloride activates S1P1-dependent p42/p44-MAPK phosphorylation. CYM5442 exerts retinal neuroprotection. CYM5442 hydrochloride can easily penetrate the central nervous system (CNS) [1][2].
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CAS Number
[1783987-80-3]
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Molecular Formula
C23H28ClN3O4
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Molecular Weight
445.94
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Smiles
CCOC1=CC=C(C2=NC(C3=CC=CC4=C3CCC4NCCO)=NO2)C=C1OCC.[H]Cl
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Target
LPL Receptor
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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CYM5442 (hydrochloride) [CAS 1783987-80-3]
CYM5442 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.