D-Arabinose [CAS 10323-20-3]
D-Arabinose [CAS 10323-20-3]
SKU:QM-0161976-01
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Product Details
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Description
D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-?Arabinose[2][3][4].
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CAS Number
[10323-20-3]
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Molecular Formula
C5H10O5
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Molecular Weight
150.13
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Smiles
O=C[C@H]([C@@H]([C@@H](CO)O)O)O
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Target
AMPK; Bacterial; Parasite; PPAR
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Isoform
Human Endogenous Metabolite; PPARγ
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Purity
99.8
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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D-Arabinose [CAS 10323-20-3]
D-Arabinose is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.