D-arabinose-13C-2
D-arabinose-13C-2
SKU:QM-0161981-01
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Product Details
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Description
D-Arabinose-13C-2 is the 13C labeled D-Arabinose. D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082)[2][3][4][5].
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Molecular Formula
C4 13CH10O5
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Molecular Weight
151.12
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Smiles
O=C[C@H]([C@@H]([13C@@H](CO)O)O)O
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Target
AMPK; Bacterial; Isotope-Labeled Compounds; Parasite; PPAR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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D-arabinose-13C-2
D-arabinose-13C-2 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.