D-Arabinose-d5
D-Arabinose-d5
SKU:QM-0161984-01
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Product Details
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Description
D-Arabinose-d5 is the deuterium labeled D-Arabinose. D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082)[2][3][4][5].
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Molecular Formula
C5H5D5O5
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Molecular Weight
155.16
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Smiles
O=C[C@@]([C@]([C@](C([2H])([2H])O)([2H])O)([2H])O)([2H])O
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Target
AMPK; Bacterial; Isotope-Labeled Compounds; Parasite; PPAR
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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D-Arabinose-d5
D-Arabinose-d5 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.