D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt)
D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt)
SKU:QM-0012794
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Product Details
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Description
D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) (Ins (1,3,4,5,6) P5 (ammonium salt) ) is an isomer of inositol phosphate that acts as a small and soluble second messenger in the transmission of cellular signals. D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) can bind to the PH domain of Grp1 with a Kd of 590 nM. D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) can inhibit the phosphorylation and kinase activity of Akt/PKB, inducing apoptosis in ovarian, lung, and breast cancer cells. D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) exhibits antiangiogenic activity in vitro and blocks capillary tube formation of HUVEC. D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) exerts antitumor effects against cancer xenografts in nude mice[1][2][3][4][5].
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Molecular Formula
C6H47N10O21P5
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Molecular Weight
750.36
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Smiles
O[C@@H]1[C@@H]([C@H]([C@@H]([C@H]([C@@H]1OP([O-])([O-])=O)OP([O-])([O-])=O)OP([O-])([O-])=O)OP([O-])([O-])=O)OP([O-])([O-])=O.[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+].[NH4+]
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Target
Akt
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Shipping Conditions
Room temperature
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D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt)
D-myo-Inositol-1,3,4,5,6-pentaphosphate (ammonium salt) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.