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Dapivirine [CAS 244767-67-7]

Dapivirine [CAS 244767-67-7]

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SKU:QM-0147815-01

£51.91 GBP
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  • Description

    Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI) . Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations[1][2].

  • CAS Number

    [244767-67-7]

  • Molecular Formula

    C20H19N5

  • Molecular Weight

    329.41

  • Smiles

    CC1=CC(C)=CC(C)=C1NC2=CC=NC(NC3=CC=C(C#N)C=C3)=N2

  • Target

    Apoptosis; Autophagy; HIV; Reverse Transcriptase

  • Isoform

    HIV-1

  • Concentration

    10mM

  • Purity

    99.8

  • Solubility

    DMSO : ≥ 47 mg/mL

  • Storage Conditions

    -20°C, 3 years; 4°C, 2 years (Powder)

  • Shipping Conditions

    Room Temperature

  • Hazard Statement

    H302, H315, H319, H335

  • Precautions

    H302, H315, H319, H335

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5 mgQM-0147815-01
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10 mM - 1 mLQM-0147815-02
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10 mgQM-0147815-03
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25 mgQM-0147815-04
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50 mgQM-0147815-05
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100 mgQM-0147815-06
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Dapivirine [CAS 244767-67-7]

Dapivirine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.