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Dapivirine [CAS 244767-67-7]
Dapivirine [CAS 244767-67-7]
SKU:QM-0147815-01
£51.91 GBP
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Product Details
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Description
Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI) . Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations[1][2].
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CAS Number
[244767-67-7]
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Molecular Formula
C20H19N5
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Molecular Weight
329.41
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Smiles
CC1=CC(C)=CC(C)=C1NC2=CC=NC(NC3=CC=C(C#N)C=C3)=N2
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Target
Apoptosis; Autophagy; HIV; Reverse Transcriptase
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Isoform
HIV-1
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Concentration
10mM
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Purity
99.8
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Solubility
DMSO : ≥ 47 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Dapivirine [CAS 244767-67-7]
Dapivirine is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.