Dapivirine-d11 [CAS 1329613-10-6]
Dapivirine-d11 [CAS 1329613-10-6]
SKU:QM-0147817
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Product Details
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Description
Dapivirine-d11 is the deuterium labeled Dapivirine. Dapivirine (TMC120), the prototype of diarylpyrimidines (DAPY), is an orally active and nonnucleoside reverse transcriptase inhibitor (NRTI) . Dapivirine (TMC120) binds directly to HIV-1 reverse transcriptase. Dapivirine (TMC120) regulates autophagy and induced Akt, Bad and SAPK/JNK activations[1][2].
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CAS Number
[1329613-10-6]
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Molecular Formula
C20H8D11N5
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Molecular Weight
340.47
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Smiles
N#CC1=CC=C(NC2=NC=CC(NC3=C(C([2H])([2H])[2H])C([2H])=C(C([2H])([2H])[2H])C([2H])=C3C([2H])([2H])[2H])=N2)C=C1
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Target
Apoptosis; Autophagy; HIV; Isotope-Labeled Compounds; Reverse Transcriptase
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Purity
0.9967
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Solubility
10 mM in DMSO
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Dapivirine-d11 [CAS 1329613-10-6]
Dapivirine-d11 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.