Dasatinib (hydrochloride) (Standard) [CAS 854001-07-3]
Dasatinib (hydrochloride) (Standard) [CAS 854001-07-3]
SKU:QM-0002498-01
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Product Details
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Description
Dasatinib (hydrochloride) (Standard) is the analytical standard of Dasatinib (hydrochloride) . This product is intended for research and analytical applications. Dasatinib (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride inhibits Bcr-Abl and Src with IC50s of [1]. Dasatinib hydrochloride also induces apoptosis and autophagy.
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CAS Number
[854001-07-3]
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Molecular Formula
C22H27Cl2N7O2S
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Molecular Weight
524.47
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Smiles
O=C(C1=CN=C(S1)NC2=NC(C)=NC(N3CCN(CC3)CCO)=C2)NC4=C(C=CC=C4Cl)C.[H]Cl
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Target
Apoptosis; Autophagy; Bcr-Abl; Reference Standards; Src
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Shipping Conditions
Room temperature
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Dasatinib (hydrochloride) (Standard) [CAS 854001-07-3]
Dasatinib (hydrochloride) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.