Dasatinib (monohydrate) (Standard) [CAS 863127-77-9]
Dasatinib (monohydrate) (Standard) [CAS 863127-77-9]
SKU:QM-0081568
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Product Details
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Description
Dasatinib (monohydrate) (Standard) is the analytical standard of Dasatinib (monohydrate) . This product is intended for research and analytical applications. Dasatinib (BMS-354825) monohydrate is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib monohydrate inhibits Bcr-Abl and Src with IC50s of [1]. Dasatinib monohydrate also induces apoptosis and autophagy.
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CAS Number
[863127-77-9]
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Molecular Formula
C22H28ClN7O3S
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Molecular Weight
506.02
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Smiles
O=C(C1=CN=C(NC2=NC(C)=NC(N3CCN(CCO)CC3)=C2)S1)NC4=C(C)C=CC=C4Cl.[H]O[H]
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Target
Apoptosis; Autophagy; Bcr-Abl; Reference Standards; Src
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Shipping Conditions
Room temperature
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Dasatinib (monohydrate) (Standard) [CAS 863127-77-9]
Dasatinib (monohydrate) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.