Dasatinib (Standard) [CAS 302962-49-8]
Dasatinib (Standard) [CAS 302962-49-8]
SKU:QM-0081570-01
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Product Details
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Description
Dasatinib (Standard) is the analytical standard of Dasatinib. This product is intended for research and analytical applications. Dasatinib (BMS-354825) is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib inhibits Bcr-Abl and Src with IC50s of [1]. Dasatinib also induces apoptosis and autophagy.
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CAS Number
[302962-49-8]
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Molecular Formula
C22H26ClN7O2S
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Molecular Weight
488.01
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Smiles
O=C(C1=CN=C(S1)NC2=NC(C)=NC(N3CCN(CC3)CCO)=C2)NC4=C(C=CC=C4Cl)C
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Target
Apoptosis; Autophagy; Bcr-Abl; Reference Standards; Src
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Shipping Conditions
Room temperature
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Hazard Statement
H315-H318-H351-H361-H372-H401-H410
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Precautions
P260-P264-P270-P273-P280-P302+P352-P362-P391-P405-P501
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Dasatinib (Standard) [CAS 302962-49-8]
Dasatinib (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.