DBCO-CONH-S-S-NHS ester [CAS 1435934-53-4]
DBCO-CONH-S-S-NHS ester [CAS 1435934-53-4]
SKU:QM-0144449-01
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Product Details
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Description
DBCO-CONH-S-S-NHS ester is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs) [1]. DBCO-CONH-S-S-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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CAS Number
[1435934-53-4]
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Molecular Formula
C28H27N3O6S2
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Molecular Weight
565.66
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Smiles
O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCSSCCC(ON4C(CCC4=O)=O)=O)=O
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Target
ADC Linker
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Isoform
Cleavable Linker; Disulfide Cleavable Linker
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Purity
99.18
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
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Shipping Conditions
Blue Ice
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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DBCO-CONH-S-S-NHS ester [CAS 1435934-53-4]
DBCO-CONH-S-S-NHS ester is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.