Dehydroepiandrosterone sulfate (sodium) (Standard) [CAS 1099-87-2]
Dehydroepiandrosterone sulfate (sodium) (Standard) [CAS 1099-87-2]
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Product Details
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Description
Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) sodium salt (Standard) is the analytical standard of Dehydroepiandrosterone sulfate sodium salt. This product is intended for research and analytical applications. Dehydroepiandrosterone sulfate (DHEA sulfate; Prasterone sulfate) is a neurosteroid and the main secretion product of the adrenal gland. Dehydroepiandrosterone sulfate has both non-competitive antagonist activity of GABAA receptor and agonist activity of σ1 receptor. Dehydroepiandrosterone sulfate can partially penetrate the blood-brain barrier, inhibit GABAA receptor-mediated chloride influx, enhance NMDA receptor activity through σ1 receptors, exert anti-inflammatory, anti-glucocorticoid and antidepressant effects, and increase convulsive sensitivity. Dehydroepiandrosterone sulfate participates in neuroprotection, neurite growth regulation and catecholamine secretion regulation, and can be used in the study of depression, post-traumatic stress disorder (PTSD), Alzheimer's disease, etc. Dehydroepiandrosterone sulfate may also be a biomarker for cardiovascular disease mortality, and its concentration is independently and negatively correlated with mortality[1][2][3][4].
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CAS Number
[1099-87-2]
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Molecular Formula
C19H27NaO5S
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Molecular Weight
390.47
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Smiles
C[C@]1([C@](CC2)([H])[C@]3([H])CC=C4C[C@@H](OS(=O)(O[Na])=O)CC[C@]4(C)[C@@]3([H])CC1)C2=O
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Target
GABA Receptor; iGluR; NF-κB; PPAR; Reference Standards; Sigma Receptor
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Isoform
PPARα; Sigma 1 Receptor
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Shipping Conditions
Room temperature
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Dehydroepiandrosterone sulfate (sodium) (Standard) [CAS 1099-87-2]
Dehydroepiandrosterone sulfate (sodium) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.