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Deoxy-thalidomide-piperidine-C-piperazine-C2-OH
Deoxy-thalidomide-piperidine-C-piperazine-C2-OH
SKU:QM-0125718
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Quantity
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Product Details
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Description
Deoxy-thalidomide-piperidine-C-piperazine-C2-OH is a conjugate of E3 ligase ligand and linker, consisting of Thalidomide and the corresponding Linker. Deoxy-thalidomide-piperidine-C-piperazine-C2-OH can serve as a Cereblon ligand to recruit CRBN protein and serve as a key intermediate for the synthesis of complete PROTAC molecules.
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Molecular Formula
C25H35N5O4
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Molecular Weight
469.58
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Smiles
O=C1NC(CCC1N2C(C3=C(C=C(C=C3)N4CCC(CC4)CN5CCN(CC5)CCO)C2)=O)=O
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Target
Apoptosis; Autophagy; E3 Ligase Ligand-Linker Conjugates
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Isoform
Cereblon
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Deoxy-thalidomide-piperidine-C-piperazine-C2-OH
Deoxy-thalidomide-piperidine-C-piperazine-C2-OH is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.