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Deschloroclozapine (dihydrochloride)
Deschloroclozapine (dihydrochloride)
SKU:QM-0156175-01
£106.00 GBP
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Product Details
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Description
Deschloroclozapine dihydrochloride, a metabolite of Clozapine, is a highly potent muscarinic DREADDs agonist. Deschloroclozapine binds to DREADD receptor subtypes hM3Dq and hM4Di with Ki of 6.3 and 4.2 nM, respectively. [11C]-Deschloroclozapine is developed as a promising PET tracer for DREADD imaging[1][2][3].
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Molecular Formula
C18H22Cl2N4
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Molecular Weight
365.3
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Smiles
CN1CCN(C2=NC3=CC=CC=C3NC4=CC=CC=C42)CC1.[H]Cl.[H]Cl
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Target
MAChR
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Purity
99.87
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Solubility
DMSO : 80 mg/mL (ultrasonic; adjust pH to 7 with 1 M NaOH) |H2O : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Blue Ice
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Deschloroclozapine (dihydrochloride)
Deschloroclozapine (dihydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.