Desmethylglycitein (Standard) [CAS 17817-31-1]
Desmethylglycitein (Standard) [CAS 17817-31-1]
SKU:QM-0024314
Request quote or documents
![Desmethylglycitein (Standard) [CAS 17817-31-1]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
Desmethylglycitein (4',6,7-Trihydroxyisoflavone), a metabolite of daidzein, sourced from Glycine max with antioxidant, and anti-cancer activities. Desmethylglycitein binds directly to CDK1 and CDK2 in vivo, resulting in the suppresses CDK1 and CDK2 activity[1]. Desmethylglycitein is a direct inhibitor of protein kinase C (PKC) α, against solar UV (sUV) -induced matrix matrix metalloproteinase 1 (MMP1) [2]. Desmethylglycitein binds to PI3K in an ATP competitive manner in the cytosol, where it inhibits the activity of PI3K and downstream signaling cascades, leading to the suppression of adipogenesis in 3T3-L1 preadipocytes[3].
-
CAS Number
[17817-31-1]
-
Molecular Formula
C15H10O5
-
Molecular Weight
270.24
-
Smiles
O=C1C(C2=CC=C(O)C=C2)=COC3=CC(O)=C(O)C=C13
-
Target
CDK; PI3K; PKC
-
Shipping Conditions
Room temperature
Related Products
- QM-0084743-01 α-Lactose (hydrate) (Standard) [CAS 5989-81-1]
- QM-0077541-01 Sucrose (Standard) [CAS 57-50-1]
- QM-0120891-01 Fructose (Standard) [CAS 7660-25-5]
- QM-0122987-01 Dihydroartemisinin (Standard) [CAS 71939-50-9]
- QM-0056024 β-Aminopropionitrile (Standard) [CAS 151-18-8]
- QM-0052524 β-Nicotinamide mononucleotide, reduced form (disodium) (Standard) [CAS 108347-85-9]
- QM-0050821 α-Tocopherol phosphate (disodium) (Standard) [CAS 60934-46-5]
- QM-0048962-01 ω-Pentadecalactone (Standard) [CAS 106-02-5]
- QM-0048660 δ-Nonalactone (Standard) [CAS 3301-94-8]
- QM-0048544 ε-Caprolactone (Standard) [CAS 502-44-3]
Other industry favorites
- QM-0084743-01 α-Lactose (hydrate) (Standard) [CAS 5989-81-1]
- QM-0077541-01 Sucrose (Standard) [CAS 57-50-1]
- QM-0005220-01 β-cyano-L-Alanine (Standard) [CAS 6232-19-5]
- QM-0004762 α-Thujone (Standard) [CAS 546-80-5]
- QM-0124545-01 δ-Decalactone (Standard) [CAS 705-86-2]
- QM-0121987-01 γ-Cyclodextrin (Standard) [CAS 17465-86-0]
- QM-0006624 β-Lactamase-IN-2 (Standard) [CAS 2114651-20-4]
- QM-0006356 ω-Hydroxy-DEET (Standard) [CAS 72236-22-7]
- QM-0168201 β-Methylcholine (chloride) (Standard) [CAS 2382-43-6]
- QM-0136206-01 γ-Tocotrienol (Standard) [CAS 14101-61-2]
Desmethylglycitein (Standard) [CAS 17817-31-1]
Desmethylglycitein (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.