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Diclofenac-13C6 (sodium heminonahydrate)

Diclofenac-13C6 (sodium heminonahydrate)

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SKU:QM-0150309-01

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  • Description

    Diclofenac-13C6 (sodium heminonahydrate) is the 13C-labeled Diclofenac Sodium. Diclofenac Sodium (GP 45840) is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac Sodium induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].

  • Molecular Formula

    13C6C8H10Cl2NNaO2.4.5H2O

  • Molecular Weight

    405.16

  • Smiles

    O=C(O[Na])C[13C]([13CH]=[13CH][13CH]=[13CH]1)=[13C]1NC2=C(C=CC=C2Cl)Cl.[4.1/2].O

  • Target

    Apoptosis; COX; Isotope-Labeled Compounds

  • Solubility

    10 mM in DMSO

  • Shipping Conditions

    Room temperature

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Diclofenac-13C6 (sodium heminonahydrate)

Diclofenac-13C6 (sodium heminonahydrate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.