Diclofenac-d4 [CAS 153466-65-0]
Diclofenac-d4 [CAS 153466-65-0]
SKU:QM-0068856-01
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Product Details
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Description
Diclofenac-d4 is the deuterium labeled Diclofenac. Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].
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CAS Number
[153466-65-0]
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Molecular Formula
C14H7D4Cl2NO2
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Molecular Weight
300.17
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Smiles
OC(CC(C([2H])=C([2H])C([2H])=C1[2H])=C1NC2=C(C=CC=C2Cl)Cl)=O
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Target
Apoptosis; COX; Isotope-Labeled Compounds
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Purity
99.79
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Solubility
10 mM in DMSO|DMSO : ≥ 30mg/mL|Ethanol : ≥ 30mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H301, H361, H373, H412
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Precautions
H301, H361, H373, H412
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Diclofenac-d4 [CAS 153466-65-0]
Diclofenac-d4 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.