Diclofenac (diethylamine) [CAS 78213-16-8]
Diclofenac (diethylamine) [CAS 78213-16-8]
SKU:QM-0150305-01
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Product Details
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Description
Diclofenac diethylamine is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells[1], and 5.1 and 0.84 μM for ovine COX-1 and COX-2, respectively[2]. Diclofenac diethylamine induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade[3].
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CAS Number
[78213-16-8]
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Molecular Formula
C18H22Cl2N2O2
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Molecular Weight
369.29
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Smiles
O=C(O)CC1=CC=CC=C1NC2=C(Cl)C=CC=C2Cl.CCNCC
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Target
Apoptosis; COX
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Isoform
COX-1; COX-2
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Purity
99.95
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Solubility
DMSO : 150 mg/mL (ultrasonic)
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Diclofenac (diethylamine) [CAS 78213-16-8]
Diclofenac (diethylamine) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.