Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate [CAS 632-93-9]
Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate [CAS 632-93-9]
SKU:QM-0139428-01
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Product Details
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Description
Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate is an orally active porphyrin inducer and ferrochelatase inhibitor. Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate can induce small bile duct obstruction in mice, resulting in blocked bile excretion and causing cholestasis. Long-term use of Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate can cause damage to bile duct epithelial cells, inflammatory responses, and liver fibrosis. Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate can be used to simulate the pathological features of cholestatic liver diseases such as sclerosing cholangitis (PSC) [1][2][3][4][5][6].
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CAS Number
[632-93-9]
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Molecular Formula
C14H21NO4
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Molecular Weight
267.32
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Smiles
CC1C(C(OCC)=O)=C(NC(C)=C1C(OCC)=O)C
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Target
Ferrochelatase
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Purity
99.83
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate [CAS 632-93-9]
Diethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.