Dimethyl fumarate [CAS 624-49-7]
Dimethyl fumarate [CAS 624-49-7]
SKU:QM-0154436-01
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Product Details
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Description
Dimethyl fumarate (DMF) is an orally active and brain-penetrant Nrf2 activator and induces upregulation of antioxidant gene expression. Dimethyl fumarate induces necroptosis in colon cancer cells through GSH depletion/ROS increase/MAPKs activation pathway, and also induces cell autophagy. Dimethyl fumarate can be used for multiple sclerosis research[1][2].
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CAS Number
[624-49-7]
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Molecular Formula
C6H8O4
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Molecular Weight
144.13
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Smiles
O=C(OC)/C=C/C(OC)=O
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Target
Autophagy; Endogenous Metabolite; HIV; Keap1-Nrf2; Reactive Oxygen Species (ROS)
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Purity
99.99
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Solubility
DMSO : 40 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Dimethyl fumarate [CAS 624-49-7]
Dimethyl fumarate is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.