Diroximel fumarate [CAS 1577222-14-0]
Diroximel fumarate [CAS 1577222-14-0]
SKU:QM-0079257-01
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Product Details
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Description
Diroximel fumarate (ALKS 8700) is an orally-active and well-tolerated monomethyl fumarate (MMF) proagent in a controlled-release formulation. Diroximel fumarate is considered as active equivalent to its active metabolite dimethyl fumarate (DMF) . Diroximel fumarate has a favorable safety and efficacy profile, has the potential for the study of multiple sclerosis (MS) . Diroximel fumarate is a Nrf2 activator that alleviate MGO-induced pain hypersensitivity[1][2].
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CAS Number
[1577222-14-0]
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Molecular Formula
C11H13NO6
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Molecular Weight
255.22
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Smiles
O=C(OCCN1C(CCC1=O)=O)/C=C/C(OC)=O
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Target
Keap1-Nrf2
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Purity
99.6
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Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : ≥ 10 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Diroximel fumarate [CAS 1577222-14-0]
Diroximel fumarate is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.