Dofequidar (fumarate) (Standard) [CAS 153653-30-6]
Dofequidar (fumarate) (Standard) [CAS 153653-30-6]
SKU:QM-0009175-01
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Product Details
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Description
Dofequidar (fumarate) (Standard) is the analytical standard of Dofequidar (fumarate) . This product is intended for research and analytical applications. Dofequidar fumarate (MS-209) is an orally active quinoline compoundthat blocks P-glycoprotein (P-gp) and multidrug resistance-associated protein-1 (MDR-1) . Dofequidar fumarate has highly potent reversing effect on multidrug-resistant tumor cells. Dofequidar fumarate competitively inhibits ABCB1/P-gp, ABCC1/MRP-1, blocks the efflux of chemotherapeutic agents, increases the drug concentration in cancer cells, and enhances the chemotherapeutic effect[1][2].
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CAS Number
[153653-30-6]
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Molecular Formula
C34H35N3O7
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Molecular Weight
597.66
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Smiles
OC(COC1=C2C=CC=NC2=CC=C1)CN3CCN(C(C(C4=CC=CC=C4)C5=CC=CC=C5)=O)CC3.O=C(O)/C=C/C(O)=O
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Target
P-glycoprotein; Reference Standards
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Shipping Conditions
Room temperature
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Dofequidar (fumarate) (Standard) [CAS 153653-30-6]
Dofequidar (fumarate) (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.