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Dolastatin 15 [CAS 123884-00-4]
Dolastatin 15 [CAS 123884-00-4]
SKU:QM-0122627
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Product Details
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Description
Dolastatin 15 (DLS 15), a depsipeptide derived from Dolabella auricularia, is a potent antimitotic agent structurally related to the antitubulin agent Dolastatin 10. Dolastatin 15 induces cell cycle arrest and apoptosis in multiple myeloma cells. Dolastatin 15 can be used as an ADC cytotoxin[1][2][3].
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CAS Number
[123884-00-4]
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Molecular Formula
C45H68N6O9
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Molecular Weight
837.06
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Smiles
O=C(N(C1=O)[C@H](C(OC)=C1)CC2=CC=CC=C2)[C@H](C(C)C)OC([C@H](CCC3)N3C([C@H](CCC4)N4C([C@H](C(C)C)N(C)C([C@H](C(C)C)NC([C@@H](N(C)C)C(C)C)=O)=O)=O)=O)=O
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Target
ADC Payload; Apoptosis; Microtubule/Tubulin
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Isoform
Auristatin
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Solubility
10 mM in DMSO
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Shipping Conditions
Room temperature
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Dolastatin 15 [CAS 123884-00-4]
Dolastatin 15 is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.