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Domatinostat [CAS 910462-43-0]
Domatinostat [CAS 910462-43-0]
SKU:QM-0076610-01
£140.88 GBP
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Product Details
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Description
Domatinostat (4SC-202 free base) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1) .
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CAS Number
[910462-43-0]
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Molecular Formula
C23H21N5O3S
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Molecular Weight
447.51
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Smiles
O=C(NC1=CC=CC=C1N)/C=C/C2=CN(S(=O)(C3=CC=C(C4=CN(C)N=C4)C=C3)=O)C=C2
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Target
Apoptosis; HDAC
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Isoform
HDAC1; HDAC10; HDAC11; HDAC2; HDAC3; HDAC5; HDAC9
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Purity
99.34
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Solubility
DMSO : ≥ 58 mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Hazard Statement
H302, H315, H319, H335
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Precautions
H302, H315, H319, H335
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Domatinostat [CAS 910462-43-0]
Domatinostat is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.