Domatinostat (tosylate) [CAS 1186222-89-8]
Domatinostat (tosylate) [CAS 1186222-89-8]
SKU:QM-0152892-01
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Product Details
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Description
Domatinostat tosylate (4SC-202) is a selective class I HDAC inhibitor with IC50 of 1.20 μM, 1.12 μM, and 0.57 μM for HDAC1, HDAC2, and HDAC3, respectively. It also displays inhibitory activity against Lysine specific demethylase 1 (LSD1) .
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CAS Number
[1186222-89-8]
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Molecular Formula
C30H29N5O6S2
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Molecular Weight
619.71
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Smiles
O=C(NC1=CC=CC=C1N)/C=C/C2=CN(S(=O)(C3=CC=C(C4=CN(C)N=C4)C=C3)=O)C=C2.O=S(C5=CC=C(C)C=C5)(O)=O
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Target
Apoptosis; HDAC
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Isoform
HDAC1; HDAC10; HDAC11; HDAC2; HDAC3; HDAC5; HDAC9
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Purity
99.66
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Solubility
DMSO : ≥ 51 mg/mL
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H315, H317, H318, H334, H335, H341, H361, H370, H413
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Precautions
H315, H317, H318, H334, H335, H341, H361, H370, H413
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Domatinostat (tosylate) [CAS 1186222-89-8]
Domatinostat (tosylate) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.