Donepezil-d4 (hydrochloride) [CAS 1219798-88-5]
Donepezil-d4 (hydrochloride) [CAS 1219798-88-5]
SKU:QM-0157430-01
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Product Details
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Description
Donepezil-d4 (hydrochloride) is the deuterium labeled Donepezil hydrochloride. Donepezil Hydrochloride (E2020) is a reversible, selective AChE inhibitor with an IC50 of 6.7 nM for AChE activity. Donepezil shows high selectivity for AChE over BuChE[1]. Donepezil exhibits neuroprotective effect on Aβ42 neurotoxicity[2].
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CAS Number
[1219798-88-5]
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Molecular Formula
C24H26D4ClNO3
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Molecular Weight
419.98
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Smiles
O=C1C2=CC(OC)=C(OC)C=C2CC1C([2H])([2H])C3CCN(CC3)C([2H])([2H])C4=CC=CC=C4.Cl
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Target
Cholinesterase (ChE)
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Purity
99.96
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Solubility
10 mM in DMSO|DMF : ≥ 1mg/mL|DMSO : ≥ 1mg/mL|Ethanol : ≥ 1mg/mL
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Donepezil-d4 (hydrochloride) [CAS 1219798-88-5]
Donepezil-d4 (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.