Doramapimod (hydrochloride) [CAS 1283526-53-3]
Doramapimod (hydrochloride) [CAS 1283526-53-3]
SKU:QM-0083102-01
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Product Details
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Description
Doramapimod hydrochloride (BIRB 796 hydrochloride) is an anti-inflammatory compound with biological activity through inhibition of p38 MAPK. Doramapimod hydrochloride can significantly inhibit the activities of TNF-α and IL-1β induced by LPS, LTA and PGN. Doramapimod hydrochloride showed a stronger inhibitory effect on inflammation induced by all three bacterial toxins, which was more significant compared with the effects of other compounds. Doramapimod hydrochloride can be used in the research of autoimmune diseases[1].
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CAS Number
[1283526-53-3]
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Molecular Formula
C31H38ClN5O3
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Molecular Weight
564.12
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Smiles
O=C(NC1=CC(C(C)(C)C)=NN1C2=CC=C(C)C=C2)NC3=C4C=CC=CC4=C(OCCN5CCOCC5)C=C3.Cl
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Target
Autophagy; p38 MAPK; Raf
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Purity
98.21
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Solubility
DMSO : 100 mg/mL (ultrasonic)
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Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
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Shipping Conditions
Room Temperature
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Doramapimod (hydrochloride) [CAS 1283526-53-3]
Doramapimod (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.