Doxepin (Hydrochloride) [CAS 1229-29-4]
Doxepin (Hydrochloride) [CAS 1229-29-4]
SKU:QM-0158840-01
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Product Details
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Description
Doxepin hydrochloride is an orally active tricyclic antidepressant agent. Doxepin hydrochloride is a potent and selective histamine receptor H1 antagonist. Doxepin hydrochloride is also a potent CYP450 inhibitor and significantly inhibits CYP450 2C19 and 1A2[1][2]. Doxepin inhibits reuptake of serotonin and norepinephrine as a tricyclic antidepressant[3].. Doxepin has therapeutic effects in atopic dermatitis, chronic urticarial, can improve cognitive processes, protect central nervous system[4].. Doxepin has also been proposed as a protective factor against oxidative stress[5]..
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CAS Number
[1229-29-4]
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Molecular Formula
C19H22ClNO
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Molecular Weight
315.84
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Smiles
CN(C)CC/C=C1C2=CC=CC=C2OCC3=CC=CC=C/13.Cl
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Target
Cytochrome P450; Histamine Receptor
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Isoform
H1 Receptor
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Purity
99.84
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Solubility
DMSO : ≥ 100 mg/mL|H2O : ≥ 50 mg/mL
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Storage Conditions
4°C (Powder, sealed storage, away from moisture)
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Shipping Conditions
Room Temperature
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Hazard Statement
H301, H361
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Precautions
H301, H361
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Doxepin (Hydrochloride) [CAS 1229-29-4]
Doxepin (Hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.