Doxorubicin (hydrochloride) [CAS 25316-40-9]
Doxorubicin (hydrochloride) [CAS 25316-40-9]
SKU:QM-0150520-01
Couldn't load pickup availability
![Doxorubicin (hydrochloride) [CAS 25316-40-9]](http://quantimol.com/cdn/shop/files/quantimol-021.png?v=1773515276&width=1445)
Product Details
-
Description
Doxorubicin hydrochloride (Hydroxydaunorubicin hydrochloride; ADR), a cytotoxic anthracycline antibiotic, is an anti-cancer chemotherapy agent. Doxorubicin hydrochloride is a potent human DNA topoisomerase I and topoisomerase II inhibitor with IC50s of 0.8 μM and 2.67 μM, respectively. Doxorubicin hydrochloride reduces basal phosphorylation of AMPK and its downstream target acetyl-CoA carboxylase. Doxorubicin hydrochloride induces apoptosis and autophagy[1][2][3].
-
CAS Number
[25316-40-9]
-
Molecular Formula
C27H30ClNO11
-
Molecular Weight
579.98
-
Smiles
COC1=C2C(C(C(C(O)=C(C[C@](C(CO)=O)(O)C[C@@H]3O[C@@]4([H])C[C@H](N)[C@H](O)[C@H](C)O4)C3=C5O)=C5C2=O)=O)=CC=C1.[H]Cl
-
Target
ADC Payload; AMPK; Antibiotic; Apoptosis; Autophagy; Bacterial; Fluorescent Dye; HBV; HIV; Mitophagy; Topoisomerase
-
Isoform
Daunorubicins/Doxorubicins; HIV-1; Topo I; Topo II
-
Purity
99.9
-
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 50 mg/mL (ultrasonic; warming; heat to 60°C)
-
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
-
Shipping Conditions
Room Temperature
-
Hazard Statement
H302, H340, H350, H360
-
Precautions
H302, H340, H350, H360
Related Products
- QM-0054453-01 Δ9-Tetrahydrocannabinolic acid [CAS 23978-85-0]
- QM-0053803 γ-Linolenic acid ethyl ester-d5
- QM-0052686-01 β-Phenyl GHB (sodium) [CAS 40951-19-7]
- QM-0051720-01 β-Phenylethyl β-D-glucoside [CAS 18997-54-1]
- QM-0049152-01 β-keto Phentermine (hydrochloride) [CAS 6946-08-3]
- QM-0048489-01 β-N-methylamino-L-alanine (hydrochloride) (Standard) [CAS 16012-55-8]
- QM-0022874 β-Prumycin hydrochloride [CAS 54612-74-7]
- QM-0008481-01 β-Methoxy 2C-B (hydrochloride) [CAS 98537-39-4]
- QM-0005999-01 β-Muricholic acid (Standard) [CAS 2393-59-1]
- QM-0161998-01 γ-Aminobutyric acid (Standard) [CAS 56-12-2]
Other industry favorites
- QM-0054453-01 Δ9-Tetrahydrocannabinolic acid [CAS 23978-85-0]
- QM-0053803 γ-Linolenic acid ethyl ester-d5
- QM-0143709-01 γ-Acetylenic GABA (hydrochloride) [CAS 103451-26-9]
- QM-0178574-01 β-Sitosterol acetate, 40% (contains Campesterol acetate) [CAS 915-05-9]
- QM-0061106-01 γ-D-Glutamylaminomethylsulfonic acid [CAS 90237-02-8]
- QM-0090052 β-Peltoboykinolic acid [CAS 24778-48-1]
- QM-0161999-01 γ-Aminobutyric acid-d6 [CAS 70607-85-1]
- QM-0162002-01 γ-Aminobutyric acid-13C4
- QM-0111443-01 β-Methylcholine (chloride) [CAS 2382-43-6]
- QM-0067514 γ-Secretase modulator 11 (hydrochloride) [CAS 2434630-30-3]
Doxorubicin (hydrochloride) [CAS 25316-40-9]
Doxorubicin (hydrochloride) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.