DPO-1 (Standard) [CAS 43077-30-1]
DPO-1 (Standard) [CAS 43077-30-1]
SKU:QM-0001985
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Product Details
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Description
DPO-1 (Standard) is the analytical standard of DPO-1. This product is intended for research and analytical applications. DPO-1 is a potent Kv1.5 and Kv1.3 (EC50 = 3.1 μM) channels inhibitor with potential immunomodulatory and anti-inflammatory effects. DPO-1 reduces Kv1.3 current density, blunts Ca2+ influx in Ca2+-depleted Jurkat cells, and inhibits IL-2 secretion in activated Jurkat cells. DPO-1 inhibits Uric acid sodium (HY-B2130A) (MSU) -induced NLRP3 inflammasome activation by blocking Kv1.5-mediated K+ efflux. DPO-1 can be used for the study of immunologic disorders and atrial fibrillation[1][2][3].
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CAS Number
[43077-30-1]
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Molecular Formula
C22H29OP
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Molecular Weight
340.44
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Smiles
CC([C@H]1[C@@H](P(C2=CC=CC=C2)(C3=CC=CC=C3)=O)C[C@H](C)CC1)C
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Target
Calcium Channel; Interleukin Related; NOD-like Receptor (NLR) ; Potassium Channel; Reference Standards
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Shipping Conditions
Room temperature
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DPO-1 (Standard) [CAS 43077-30-1]
DPO-1 (Standard) is a premium-grade research compound supplied by Quantimol for laboratory and scientific applications.